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Agammaglobulinaemia and Selective Immunoglobulin Isotype Deficiencies
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Epidemiological Studies research papers
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A 9 page
paper discussing X-linked agammaglobulinaemia (XLA), an immunodeficiency in which
mature B lymphocyte cells fail to develop and Ig heavy chain rearrangement fails to
progress as it should. The paper also discusses X-linked Hyper IgM Syndrome. Both
conditions can result in decreased levels of IgA, IgG and IgE. XLA has been associated
with greater incidence of colorectal cancer in young adults, but researchers are unclear
whether the increase is related to a life history of greater incidence of infection. Many XLA
patients died before reaching their 20s and 30s in years past, but better treatments are
improving their chances. Includes 2 figures, bibliography lists 11 sources.
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Pages:
9
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Filename:CC6_KSAgamma.doc |
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Paper Title:
Agammaglobulinaemia and Selective Immunoglobulin Isotype Deficiencies
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